多哈毛孢子菌致急性髓细胞白血病患儿真菌性血流感染1例
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A case of fungal bloodstream infection caused by Trichosporon dohaense in a pediatric patient with acute myeloid leukemia
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    摘要:

    本文报告1例急性髓细胞白血病(AML)患儿罹患多哈毛孢子菌血流感染病例。该病例血培养采用VITEK MS质谱仪无法鉴定病原体,采用VITEK Ⅱ YST系统将其错误鉴定为阿萨希毛孢子菌,最终经分子测序准确鉴定为多哈毛孢子菌。本例患儿(1-3)-β-D葡聚糖检测(G试验)结果在正常范围,经临床积极的抗真菌感染治疗后患儿好转出院。因此,对于多哈毛孢子菌血流感染的粒细胞缺乏患者,临床需积极进行抗真菌感染治疗,谨慎解读G试验结果,进一步加强对该少见真菌的认识。

    Abstract:

    This paper reports a pediatric patient with acute myeloid leukemia (AML) who developed bloodstream infection (BSI) caused by Trichosporon dohaense (T. dohaense). The pathogen in the blood culture of this case could not be identified by VITEK MS mass spectrometer; it was mistakenly identified as T.asahii by the VITEK Ⅱ YST system, and was ultimately accurately identified as T. dohaense through molecular sequencing. The (1-3)-β-D-glucan test (G test) result for this pediatric patient was within the normal range. The patient recovered and was discharged after active clinical antifungal treatment. Therefore, for T. dohaense BSI patients with granulocytopenia, it is necessary to actively administer antifungal treatment in clinical practice, carefully interpret G test results, and further strengthen the understanding of this rare fungus.

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李雄斌,袁凯旋.多哈毛孢子菌致急性髓细胞白血病患儿真菌性血流感染1例[J]. 中国感染控制杂志,2025,24(4):568-570. DOI:10.12138/j. issn.1671-9638.20256838.
LI Xiongbin, YUAN Kaixuan. A case of fungal bloodstream infection caused by Trichosporon dohaense in a pediatric patient with acute myeloid leukemia[J]. Chin J Infect Control, 2025,24(4):568-570. DOI:10.12138/j. issn.1671-9638.20256838.

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  • 收稿日期:2024-08-06
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  • 在线发布日期: 2025-04-24
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